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Structure of 2411405-92-8
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This difluorocyclopropaneboronic ester features a strained cyclopropyl ring bearing two fluorine atoms and a boronate functionality, enabling direct incorporation into cross-coupling reactions. The pinacol protection enhances stability and solubility in organic media, facilitating handling and integration into synthetic sequences.
2,2-Difluoro-cyclopropaneboronic acid pinacol ester serves as a stable, bench-ready building block for the incorporation of fluorinated cyclopropane motifs into complex molecular architectures. Its robust pinacol boronate ester functionality enables reliable Suzuki-Miyaura cross-coupling reactions under standard conditions, offering high functional group tolerance and predictable stereochemical transfer. This reagent facilitates efficient access to fluorinated heterocycles and medicinal chemistry scaffolds, particularly in applications requiring metabolic stability and conformational rigidity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: