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1-Piperidinecarboxylic acid, 2-methyl-4-oxo-, 1,1-dimethylethyl ester, (2S)-

  • CAS No. 790667-49-1

  • Cat. No. CS-0030787
  • Purity≥97%
  • MDL No.MFCD09832895
  • HazMat Fee +

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

1-Piperidinecarboxylic acid, 2-methyl-4-oxo-, 1,1-dimethylethyl ester, (2S)-|CS-0030787

Structure of 790667-49-1

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Description

This tert-butyl ester derivative of (2S)-2-methyl-4-oxopiperidine-1-carboxylic acid features a chiral, bench-stable scaffold with a protected carboxylic acid. The piperidine core bears a ketone at C4 and a methyl group at C2, enabling direct incorporation into complex heterocycles. Its robust stability under standard conditions supports efficient use in synthetic sequences requiring selective transformations.

Application

(2S)-2-Methyl-4-oxo-piperidine-1-carboxylic acid tert-butyl ester serves as a versatile chiral building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its tert-butyl carbamate group enables facile deprotection under mild acidic conditions, while the 4-oxo functionality supports nucleophilic addition and reductive amination reactions. The (2S)-configuration provides stereocontrol in asymmetric synthesis, and the compound exhibits excellent bench stability and compatibility with standard purification methods.

General Information

  • CAS No. 790667-49-1
  • Cat. No. CS-0030787
  • Purity ≥97%
  • MDL No. MFCD09832895
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉NO₃
  • Molecular Weight 213.27
  • Synonym(s) 1-Piperidinecarboxylicacid, 2-methyl-4-oxo-, 1,1-dimethylethyl ester, (2S)-
  • SMILES O=C(OC(C)(C)C)N1[C@H](CC(CC1)=O)C

Computational Chemistry Data

  • TPSA   46.61
  • LogP   1.9749
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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