Amino-3,5-dibromopyrazine

CAS No. 24241-18-7
Cat. No. CS-D1346
Purity≥96%
MDL No.MFCD00673150

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Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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Description

Amino-3,5-dibromopyrazine features a pyrazine core functionalized with amino and dibromo substituents, enabling direct incorporation into heterocyclic scaffolds. The electron-deficient ring system facilitates cross-coupling reactions under standard conditions, while the bromine atoms serve as reactive handles for further derivatization. This compound offers high stability and predictable reactivity in synthetic sequences.

Application

Amino-3,5-dibromopyrazine serves as a versatile building block for the synthesis of functionalized heterocycles and pharmaceutical intermediates. Its dual bromo groups enable efficient palladium-catalyzed cross-coupling reactions, while the amino functionality offers site-specific derivatization. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.

General Information

CAS No. 24241-18-7
Cat. No. CS-D1346
Purity ≥96%
MDL No. MFCD00673150
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₃Br₂N₃
Molecular Weight 252.89
Synonym(s) 3,5-Dibromo-2-pyrazinamine; 3,5-Dibromopyrazin-2-ylamine
SMILES BrC1=NC(Br)=C(N)N=C1

Computational Chemistry Data

TPSA 51.8
LogP 1.5838
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS05,GHS06
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301-H315-H318-H335
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Building Blocks Functional Group Amine

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazine compounds

Key Words

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Amino-3,5-dibromopyrazine

CAS No. 24241-18-7

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