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CS-W001157 4
Total: USD 88.00

4-Amino-N-[4-(trifluoromethyl)phenyl]benzenesulfonamide

  • CAS No. 339-42-4

  • Cat. No. CS-0207069
  • Molecule weight316.30
  • Purity≥98%
  • MDL No.MFCD01935804

*For research and further manufacturing use only, not for direct human use.

4-Amino-N-[4-(trifluoromethyl)phenyl]benzenesulfonamide|CS-0207069

Structure of 339-42-4

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General Information

  • CAS No. 339-42-4
  • Cat. No. CS-0207069
  • Purity ≥98%
  • MDL No. MFCD01935804
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₁F₃N₂O₂S
  • Molecular Weight 316.30
  • Synonym(s) 4-Amino-N-[4-(trifluoromethyl)-phenyl]benzenesulfonamide
  • SMILES C1=C(C=CC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N)C(F)(F)F

Synthesis

  • Route1
    • 4-Nitro-n-(4-(trifluoromethyl)phenyl)benzenesulfonamide|CS-0662313
      312-51-6
    • ~80%
    • 4-Amino-N-[4-(trifluoromethyl)phenyl]benzenesulfonamide|CS-0207069
      339-42-4

    References

    • Zheng, Xiaoxia; Oda, Hiroyuki; Takamatsu, Kayo; Sugimoto, Yukio; Tai, Akihiro; Akaho, Eiichi; Ali, Hamed Ismail; Oshiki, Toshiyuki; Kakuta, Hiroki; Sasaki, Kenji Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 2 p. 1014 - 1021
  • Route2
    • 4-(Trifluoromethyl)aniline Leflunomide Impurity|CS-0229655
      455-14-1
    • ~%
    • 4-Amino-N-[4-(trifluoromethyl)phenyl]benzenesulfonamide|CS-0207069
      339-42-4

    References

    • Zhang, Guangtao; Plotnikov, Alexander N.; Rusinova, Elena; Shen, Tong; Morohashi, Keita; Joshua, Jennifer; Zeng, Lei; Mujtaba, Shiraz; Ohlmeyer, Michael; Zhou, Ming-Ming Journal of Medicinal Chemistry, 2013 , vol. 56, # 22 p. 9251 - 9264
  • Route3
    • null|null
      98-74-8
    • ~%
    • 4-Amino-N-[4-(trifluoromethyl)phenyl]benzenesulfonamide|CS-0207069
      339-42-4

    References

    • Zhang, Guangtao; Plotnikov, Alexander N.; Rusinova, Elena; Shen, Tong; Morohashi, Keita; Joshua, Jennifer; Zeng, Lei; Mujtaba, Shiraz; Ohlmeyer, Michael; Zhou, Ming-Ming Journal of Medicinal Chemistry, 2013 , vol. 56, # 22 p. 9251 - 9264

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312+H332-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   72.19
  • LogP   3.0884
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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