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Structure of 341-23-1
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4-Fluoro-1H-indazole is a fluorinated heterocyclic scaffold featuring a nitrogen-rich core with enhanced electron deficiency. This structural motif integrates readily into bioactive molecules, offering improved metabolic stability and membrane permeability. The para-fluorine substitution enables strong dipole interactions in target binding pockets. Ideal for medicinal chemistry campaigns requiring precise electronic tuning and favorable physicochemical properties.
4-Fluoro-1H-indazole serves as a versatile heterocyclic building block in medicinal chemistry, enabling direct functionalization at the C4 position via palladium-catalyzed cross-coupling reactions. Its fluorinated aromatic core provides enhanced metabolic stability and modulates electronic properties for target engagement. The compound exhibits excellent bench stability, ease of purification, and compatibility with diverse reaction conditions, making it a practical scaffold for developing kinase inhibitors and CNS-targeted therapeutics.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: