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Structure of 408359-52-4
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1-(3-Cyclopropylphenyl)ethanone features a cyclopropyl-substituted aromatic ring linked to a ketone functional group, delivering enhanced lipophilicity and metabolic stability. This scaffold integrates readily into medicinal chemistry campaigns targeting CNS-active compounds and kinase inhibitors. The sterically constrained cyclopropyl moiety imparts conformational rigidity, improving binding affinity in target-directed synthesis.
1-(3-Cyclopropylphenyl)ethanone serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive scaffolds through standard carbonyl transformations. Its cyclopropyl-substituted aryl ketone functionality offers enhanced metabolic stability and tunable lipophilicity. The compound exhibits excellent bench stability, facilitates straightforward purification, and participates reliably in nucleophilic additions, reductions, and coupling reactions under routine laboratory conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: