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CS-W001157 4
Total: USD 88.00

5-((4-Bromo-2-chlorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylic acid

  • CAS No. 606144-04-1

  • Cat. No. CS-M0259
  • Molecule weight398.61
  • Purity≥95%
  • MDL No.MFCD09953722

*For research and further manufacturing use only, not for direct human use.

5-((4-Bromo-2-chlorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylic acid|CS-M0259

Structure of 606144-04-1

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General Information

  • CAS No. 606144-04-1
  • Cat. No. CS-M0259
  • Purity ≥95%
  • MDL No. MFCD09953722
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₀BrClFN₃O₂
  • Molecular Weight 398.61
  • Synonym(s) 6-(4-Bromo-2-chlorophenylamino)-7-fluoro-3-methyl-benzimidazole-5-carboxylic acid
  • SMILES O=C(O)C1=C(NC(C=C2)=C(Cl)C=C2Br)C(F)=C3N=CN(C)C3=C1

Synthesis

  • Route1
    • Methyl 5-((4-bromo-2-chlorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate|CS-M0258
      606144-02-9
    • ~79%
    • In-stock
      5-((4-Bromo-2-chlorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylic acid|CS-M0259
      606144-04-1

    References

    • Wallace, Eli M.; Lyssikatos, Joseph P.; Marlow, Allison L.; Hurley, T. Brian Patent: US2003/232869 A1, 2003 ; Location in patent: Page 10; 22; 23 ; US 20030232869 A1
  • Route2

    References

    • ARRAY BIOPHARMA INC.; ASTRAZENECA AB Patent: WO2007/2157 A2, 2007 ; Location in patent: Page/Page column 73; 74 ; WO 2007/002157 A2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   67.15
  • LogP   4.5701
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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