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Structure of 632325-50-9
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Ethyl 2-bromothiophene-3-carboxylate features a brominated thiophene core with an ester-functionalized side chain, enabling direct incorporation into cross-coupling reactions. The electron-deficient thiophene ring facilitates palladium-catalyzed transformations, while the ethyl ester group offers tunable reactivity and stability under standard conditions. This compound serves as a key intermediate in synthesizing biologically active heterocycles and functional materials.
Ethyl 2-bromothiophene-3-carboxylate serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of biologically relevant thiophene-based scaffolds. The bromo group facilitates reliable C–C bond formation under standard Suzuki, Stille, and Negishi conditions, while the ester functionality supports subsequent transformations such as hydrolysis or reduction. Its bench stability and compatibility with diverse functional groups make it a practical choice for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: