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CS-W001157 4
Total: USD 88.00

4-Pyridineacetic acid hydrochloride

  • CAS No. 6622-91-9

  • Cat. No. CS-W002081
  • Molecule weight173.60
  • Purity≥97%
  • MDL No.MFCD00012827

*For research and further manufacturing use only, not for direct human use.

4-Pyridineacetic acid hydrochloride|CS-W002081

Structure of 6622-91-9

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General Information

  • CAS No. 6622-91-9
  • Cat. No. CS-W002081
  • Purity ≥97%
  • MDL No. MFCD00012827
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈ClNO₂
  • Molecular Weight 173.60
  • Synonym(s) pyridin-4-ylacetate; 4-Pyridineacetic acid hydrochloride
  • SMILES OC(=O)Cc1ccncc1.Cl

Description

4-Pyridineacetic acid hydrochloride offers a robust pyridine scaffold with a carboxylic acid functionality, enabling direct conjugation or derivatization in synthetic workflows. The hydrochloride salt enhances solubility and stability under standard handling conditions, facilitating integration into pharmaceutical intermediates, ligand design, and bioconjugation strategies.

Application

4-Pyridineacetic acid hydrochloride serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyridine-containing bioactive molecules. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions under standard conditions. The hydrochloride salt enhances bench stability and solubility in polar solvents, simplifying handling and purification. Functions effectively in peptide extensions, heterocycle functionalization, and scaffold diversification for drug discovery applications.

Synthesis

  • Route1
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    • In-stock
      4-Pyridineacetic acid hydrochloride|CS-W002081
      6622-91-9

    References

    • European Journal of Medicinal Chemistry, , vol. 17, # 6 p. 531 - 535
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      4-Pyridineacetic acid hydrochloride|CS-W002081
      6622-91-9

    References

    • European Journal of Medicinal Chemistry, , vol. 17, # 6 p. 531 - 535

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.1305
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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