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Structure of 766-11-0
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5-Bromo-2-fluoropyridine is a halogenated pyridine derivative featuring complementary reactive sites for cross-coupling and functionalization. The electron-deficient ring enables efficient palladium-catalyzed transformations, while the fluorine and bromine substituents offer orthogonal reactivity in synthetic sequences. This bench-stable compound integrates seamlessly into complex molecule assembly.
5-Bromo-2-fluoropyridine serves as a versatile building block in medicinal chemistry and cross-coupling synthesis. Its dual halogen functionality enables sequential Pd-catalyzed transformations, with the bromide typically reacting first under standard Suzuki or Buchwald-Hartwig conditions. The fluorine substituent enhances metabolic stability and modulates electronic properties, while the compound exhibits good bench stability and compatibility with common purification methods.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H227-H315-H319-H335
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Precautionary Statements : P210-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P403-P405-P501
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Lot numbers can be found on the outside label of a product: