2-Hydroxy-4-methoxybenzaldehyde

CAS No. 673-22-3
Cat. No. CS-D1182
Purity≥97%
MDL No.MFCD00003327

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2-Hydroxy-4-methoxybenzaldehyde|CS-D1182

Structure of 673-22-3

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Description

2-Hydroxy-4-methoxybenzaldehyde is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants.2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.

Application

2-Hydroxy-4-methoxybenzaldehyde serves as a versatile building block in synthetic organic chemistry, enabling efficient access to bioactive heterocycles and natural product analogs. Its ortho-hydroxyl and para-methoxy substituents provide complementary functionality for directed metalation, electrophilic substitution, and coupling reactions. The aldehyde group facilitates reductive amination, Schiff base formation, and Ullmann-type condensations. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses requiring functional group tolerance and predictable reactivity.

General Information

CAS No. 673-22-3
Cat. No. CS-D1182
Purity ≥97%
MDL No. MFCD00003327
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₈O₃
Molecular Weight 152.15
Synonym(s) None
SMILES O=CC1=CC=C(OC)C=C1O

Computational Chemistry Data

TPSA 46.53
LogP 1.2133
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 2

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Bioactive Molecules Natural Products

Building Blocks Functional Group Phenol

Building Blocks Functional Group Aldehyde

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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2-Hydroxy-4-methoxybenzaldehyde

CAS No. 673-22-3

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