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Structure of 690636-28-3
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This morpholine derivative features a boronate ester handle for reliable Suzuki-Miyaura coupling, enabling efficient incorporation into complex molecular architectures. The ethylene linker provides conformational flexibility, while the para-phenoxy substitution enhances electronic communication. Bench-stable under standard conditions, it streamlines late-stage functionalization in medicinal chemistry and materials synthesis.
4-(2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)ethyl)morpholine serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The tetramethyl-1,3,2-dioxaborolane moiety enables stable, bench-ready coupling with aryl halides under mild conditions. The morpholine ether functionality provides solubility and metabolic stability, while the ethylene linker offers flexibility in scaffold construction. This reagent facilitates efficient access to biaryl and heteroaryl architectures common in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: