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Structure of 7151-76-0
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4-(Methylsulfonamido)benzoic acid features a para-substituted aromatic core with a sulfonamide group linked to a methyl moiety and a carboxylic acid functionality. This combination enables robust hydrogen bonding and polarity, facilitating integration into bioactive scaffolds and enabling solubility in polar media under standard conditions.
4-(Methylsulfonamido)benzoic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and pharmaceutical scaffolds. Its dual functionality—carboxylic acid and sulfonamide groups—facilitates diverse coupling reactions, including amide formation and amidation, while maintaining excellent bench stability and ease of purification. The molecule exhibits good solubility in common organic solvents and demonstrates robust functional group tolerance, making it well-suited for multi-step synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: