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Structure of 6952-59-6
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3-Bromobenzonitrile features a bromine substituent at the meta position relative to a nitrile group on a benzene ring, enabling selective coupling reactions in pharmaceutical synthesis. This configuration imparts enhanced stability and facilitates directed functionalization in cross-coupling processes under standard conditions.
3-Bromobenzonitrile serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Stille couplings. Its bromine and nitrile functionalities offer orthogonal reactivity for sequential functionalization. The compound exhibits good bench stability, facilitates straightforward purification by distillation or recrystallization, and functions efficiently in the synthesis of heterocyclic scaffolds and biaryl architectures relevant to pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302+H312+H332-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: