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Structure of 703-91-3
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5-Bromo-2-(trifluoromethyl)aniline features a trifluoromethyl group that imparts enhanced electron-withdrawal and metabolic stability, while the bromo substituent enables facile cross-coupling transformations. This bench-stable aryl amine integrates efficiently into pharmaceutical intermediates and functional materials under standard conditions.
5-Bromo-2-(trifluoromethyl)aniline serves as a versatile building block in medicinal chemistry and materials science, enabling efficient Suzuki-Miyaura and Buchwald-Hartwig coupling reactions. The bromo group provides high reactivity in palladium-catalyzed cross-couplings, while the trifluoromethyl moiety enhances metabolic stability and lipophilicity. Bench-stable and readily purified by column chromatography, it facilitates the construction of complex heterocyclic scaffolds and functionalized aryl architectures common in API development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: