4-Chloro-2-methyl-6-nitroquinazoline

CAS No. 74151-22-7
Cat. No. CS-0152824
Purity≥97%
MDL No.MFCD11047030

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Chloro-2-methyl-6-nitroquinazoline|CS-0152824

Structure of 74151-22-7

Size

Price

Quantity

* Please select Quantity before adding items.

Description

4-Chloro-2-methyl-6-nitroquinazoline features a fused bicyclic core with electron-withdrawing nitro and chloro substituents positioned for enhanced reactivity in cross-coupling and medicinal chemistry applications. The methyl group at the 2-position provides steric control, while the para-nitro functionality enables facile derivatization. This compound serves as a key scaffold for kinase inhibitor development and exhibits favorable stability under standard bench conditions.

Application

4-Chloro-2-methyl-6-nitroquinazoline serves as a versatile building block in medicinal chemistry, enabling efficient access to kinase-inhibitor scaffolds. Its ortho-chloro and nitro groups facilitate palladium-catalyzed cross-coupling and selective reduction, while the methyl group enhances metabolic stability. The compound exhibits excellent bench stability and compatibility with standard purification protocols, making it well-suited for modular synthesis of bioactive quinazoline derivatives.

General Information

CAS No. 74151-22-7
Cat. No. CS-0152824
Purity ≥97%
MDL No. MFCD11047030
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₆ClN₃O₂
Molecular Weight 223.62
Synonym(s) None
SMILES CC1=NC(=C2C=C(C=CC2=N1)[N+](=O)[O-])Cl

Computational Chemistry Data

TPSA 68.92
LogP 2.49982
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Nitro compounds

Building Blocks Skeleton Aromatic heterocycle compounds Quinazoline compounds

Key Words

4-Chloro-2-methyl-6-nitroquinazoline sigma4-Chloro-2-methyl-6-nitroquinazoline manufacturer4-Chloro-2-methyl-6-nitroquinazoline price4-Chloro-2-methyl-6-nitroquinazoline structure4-Chloro-2-methyl-6-nitroquinazoline SDSbuy 4-Chloro-2-methyl-6-nitroquinazoline4-Chloro-2-methyl-6-nitroquinazoline supplier4-Chloro-2-methyl-6-nitroquinazoline uses4-Chloro-2-methyl-6-nitroquinazoline molecular weightprice of 4-Chloro-2-methyl-6-nitroquinazoline4-Chloro-2-methyl-6-nitroquinazoline chemical name formula of 4-Chloro-2-methyl-6-nitroquinazoline

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-Chloro-2-methyl-6-nitroquinazoline

CAS No. 74151-22-7

Recommended Products