2,2-Dimethyl-1,3-dioxan-5-one

CAS No. 74181-34-3
Cat. No. CS-W006362
Purity≥96%
MDL No.MFCD00671514

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2,2-Dimethyl-1,3-dioxan-5-one|CS-W006362

Structure of 74181-34-3

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 74181-34-3
Cat. No. CS-W006362
Purity ≥96%
MDL No. MFCD00671514
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₀O₃
Molecular Weight 130.14
Synonym(s) 2,2-DIMETHYL-1,3-DIOXANE-5-ONE
SMILES O=C1COC(C)(C)OC1

Description

This cyclic β-ketoester features a sterically hindered dimethyl substitution at the 2-position, enhancing stability and reducing unwanted side reactions. The 1,3-dioxan-5-one core provides a rigid, electron-deficient framework ideal for Diels-Alder cycloadditions and as a masked acyl equivalent in synthetic transformations.

Application

2,2-Dimethyl-1,3-dioxan-5-one serves as a stable, bench-ready synthon for the construction of complex carbocycles and heterocyclic frameworks. Its α,α-dimethyl substitution enhances kinetic stability while maintaining reactivity toward nucleophiles, enabling regioselective ring-opening reactions. Functions effectively in Grignard additions and reductions, providing access to substituted tetrahydrofurans and diol derivatives with predictable stereochemistry. Ideal for iterative synthesis workflows requiring robust, functional group-tolerant intermediates.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS02
Signal Word : Danger	UN#: 1993
Class : 3	Packing Group : Ⅲ
Hazard Statements : H225
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P370+P378-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 35.53
LogP 0.3384
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Key Words

2,2-Dimethyl-1,3-dioxan-5-one sigma2,2-Dimethyl-1,3-dioxan-5-one manufacturer2,2-Dimethyl-1,3-dioxan-5-one price2,2-Dimethyl-1,3-dioxan-5-one structure2,2-Dimethyl-1,3-dioxan-5-one SDSbuy 2,2-Dimethyl-1,3-dioxan-5-one2,2-Dimethyl-1,3-dioxan-5-one supplier2,2-Dimethyl-1,3-dioxan-5-one uses2,2-Dimethyl-1,3-dioxan-5-one molecular weightprice of 2,2-Dimethyl-1,3-dioxan-5-one2,2-Dimethyl-1,3-dioxan-5-one chemical name formula of 2,2-Dimethyl-1,3-dioxan-5-one

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2,2-Dimethyl-1,3-dioxan-5-one

CAS No. 74181-34-3

Recommended Products