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Structure of 4728-12-5
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This bench-stable, moisture-tolerant acetal alcohol features a rigid five-membered dioxane ring that enhances solubility in polar aprotic solvents. The primary hydroxyl group enables straightforward derivatization, while the gem-dimethyl substitution prevents undesired ring-opening under standard conditions. Ideal for protecting group strategies and synthetic intermediates requiring stability during multi-step transformations.
(2,2-Dimethyl-1,3-dioxan-5-yl)methanol serves as a stable, bench-friendly synthon for the introduction of protected diol motifs in complex molecule synthesis. Its rigid dioxane ring imparts enhanced stability and predictable stereochemistry, while the primary alcohol functionality enables straightforward derivatization via esterification, etherification, or coupling reactions. The geminal dimethyl groups provide steric shielding, minimizing side reactions and facilitating purification. This compound functions effectively in multistep sequences involving protecting group strategies, heterocyclic construction, and late-stage functionalization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: