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CS-W001157 4
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4-(4-(4-(4-Methoxyphenyl)piperazin-1-yl)phenyl)-4H-1,2,4-triazol-3-ol

  • CAS No. 74853-07-9

  • Cat. No. CS-0326470
  • Molecule weight351.40
  • Purity95+%
  • MDL No.MFCD02956606

*For research and further manufacturing use only, not for direct human use.

4-(4-(4-(4-Methoxyphenyl)piperazin-1-yl)phenyl)-4H-1,2,4-triazol-3-ol|CS-0326470

Structure of 74853-07-9

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General Information

  • CAS No. 74853-07-9
  • Cat. No. CS-0326470
  • Purity 95+%
  • MDL No. MFCD02956606
  • Storage RT, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₂₁N₅O₂
  • Molecular Weight 351.40
  • Synonym(s) 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one
  • SMILES COC1=CC=C(C=C1)N2CCN(CC2)C3=CC=C(C=C3)N4C=NN=C4O

Synthesis

  • Route1
    • Itraconazole impurity 16|CS-0807795
      74852-89-4
    • null|null
      143-37-3
    • ~28%
    • In-stock
      4-(4-(4-(4-Methoxyphenyl)piperazin-1-yl)phenyl)-4H-1,2,4-triazol-3-ol|CS-0326470
      74853-07-9

    References

    • JANSSEN PHARMACEUTICA N.V. Patent: WO2006/67139 A1, 2006 ; Location in patent: Page/Page column 34 ; WO 2006/067139 A1
  • Route2
    • 1-(4-Methoxyphenyl)piperazine Miconazole  Impurity|CS-0229176
      38212-30-5
    • ~%
    • In-stock
      4-(4-(4-(4-Methoxyphenyl)piperazin-1-yl)phenyl)-4H-1,2,4-triazol-3-ol|CS-0326470
      74853-07-9

    References

    • Journal of Medicinal Chemistry, , vol. 27, # 7 p. 894 - 900
  • Route3
    • null|null
      100-00-5
    • ~%
    • In-stock
      4-(4-(4-(4-Methoxyphenyl)piperazin-1-yl)phenyl)-4H-1,2,4-triazol-3-ol|CS-0326470
      74853-07-9

    References

    • Journal of Medicinal Chemistry, , vol. 27, # 7 p. 894 - 900

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   66.65
  • LogP   2.3081
  • H_Acceptors   7
  • H_Donors   1
  • Rotatable_Bonds   4

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