1,2,4-Thiadiazol-5-amine

CAS No. 7552-07-0
Cat. No. CS-0037734
Purity≥97%
MDL No.MFCD01102171

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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Description

1,2,4-Thiadiazol-5-amine features a heterocyclic core with nitrogen and sulfur atoms that imparts enhanced stability and hydrogen-bonding capacity. This scaffold integrates readily into bioactive molecules, serving as a key pharmacophore in medicinal chemistry. The amine group enables direct derivatization, while the electron-deficient ring facilitates interactions with biological targets.

Application

1,2,4-Thiadiazol-5-amine serves as a versatile heterocyclic building block in medicinal chemistry and materials science. Its nitrogen-rich core enables robust metal coordination and enhances molecular polarity, facilitating purification and crystallization. The amine functionality supports diverse derivatization via amidation, alkylation, and coupling reactions, making it valuable for constructing bioactive scaffolds and functional polymers. Bench-stable and readily handled, it functions reliably in standard synthetic workflows.

General Information

CAS No. 7552-07-0
Cat. No. CS-0037734
Purity ≥97%
MDL No. MFCD01102171
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂H₃N₃S
Molecular Weight 101.13
Synonym(s) 5-Amino-1,2,4-thiadiazole
SMILES NC1=NC=NS1

Computational Chemistry Data

TPSA 51.8
LogP 0.1203
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Thiadiazole compounds

Key Words

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1,2,4-Thiadiazol-5-amine

CAS No. 7552-07-0

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