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CS-W001157 4
Total: USD 88.00

Methyl aminolevulinate hydrochloride

  • CAS No. 79416-27-6

  • Cat. No. CS-W009212
  • Molecule weight181.62
  • Purity≥95%
  • MDL No.MFCD00012868

*For research and further manufacturing use only, not for direct human use.

Methyl aminolevulinate hydrochloride|CS-W009212

Structure of 79416-27-6

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General Information

  • CAS No. 79416-27-6
  • Cat. No. CS-W009212
  • Purity ≥95%
  • MDL No. MFCD00012868
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClNO₃
  • Molecular Weight 181.62
  • Synonym(s) 5-Aminolevulinic Acid Methyl Ester Hydrochloride;Methyl 5-amino-4-oxopentanoate hydrochloride
  • SMILES O=C(OC)CCC(CN)=O.[H]Cl

Description

Methyl aminolevulinate hydrochloride is a photosensitizing agent that integrates into cellular metabolic pathways, delivering targeted photodynamic activity. This bench-stable derivative enables efficient activation under light exposure, supporting precise therapeutic applications in dermatological treatments.

Application

Methyl aminolevulinate (hydrochloride) serves as a well-characterized prodrug precursor in photodynamic therapy, enabling selective intracellular generation of protoporphyrin IX. Its stability under standard laboratory conditions and compatibility with aqueous-based formulations facilitate reliable use in dermatological applications. The compound functions as a key intermediate in the synthesis of porphyrin-based photosensitizers, offering predictable reactivity and ease of handling during formulation development.

Synthesis

  • Route1

    References

    • US6034267 A1, ;
  • Route2
    • null|null
      67-56-1
    • In-stock
      5-Aminolevulinic acid hydrochloride|CS-2575
      5451-09-2
    • ~89%
    • In-stock
      Methyl aminolevulinate hydrochloride|CS-W009212
      79416-27-6

    References

    • Dabrowski, Zbigniew; Kwasny, Miroslaw; Kaminski, Jaroslaw; Beldowicz, Maria; Lewicka, Lidia; Obukowicz, Bozena; Kaliszewski, Miron; Pirozynska, Ewa Acta Poloniae Pharmaceutica - Drug Research, 2003 , vol. 60, # 3 p. 219 - 224
  • Route3
    • null|null
      67-56-1
    • In-stock
      5-Aminolevulinic acid|CS-W000450
      106-60-5
    • ~%
    • In-stock
      Methyl aminolevulinate hydrochloride|CS-W009212
      79416-27-6

    References

    • Photochemistry and Photobiology, , vol. 74, # 5 p. 721 - 725

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   69.39
  • LogP   -0.1108
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   4

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