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Structure of 80410-57-7
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3-Methoxy-4-nitrobenzaldehyde features a para-nitro group and a methoxy substituent flanking the aldehyde functionality, delivering enhanced electron-withdrawing character and improved solubility. This combination enables efficient coupling in cross-coupling reactions and facilitates the synthesis of complex aromatic scaffolds under standard conditions.
3-Methoxy-4-nitrobenzaldehyde serves as a versatile building block in medicinal chemistry and materials science, enabling efficient access to functionalized aromatic systems. Its ortho-methoxy and para-nitro substituents provide complementary reactivity for electrophilic substitution, nucleophilic addition, and transition-metal-catalyzed coupling reactions. The aldehyde group facilitates imine formation, reductive amination, and condensation reactions, while the nitro group supports subsequent reduction to aniline derivatives. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses of heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: