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Structure of 5081-37-8
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Methyl 3-methoxy-4-nitrobenzoate features a nitro group at the para position relative to the ester, enhancing electron deficiency for nucleophilic substitution. The methoxy substituent provides steric and electronic modulation, improving solubility in organic solvents. This compound serves as a key intermediate in synthesizing bioactive heterocycles and functionalized aromatics under standard conditions.
Methyl 3-methoxy-4-nitrobenzoate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized aromatic scaffolds. Its ortho-methoxy and para-nitro substituents provide complementary reactivity for selective transformations, including nitro reduction, ester hydrolysis, and coupling reactions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: