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Structure of 82420-35-7
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2-(Bromomethyl)-4-fluoro-1-nitrobenzene features a bromomethyl group flanked by electron-withdrawing nitro and fluoro substituents, enabling selective functionalization in late-stage diversification. This electrophilic handle integrates readily into cross-coupling and nucleophilic substitution cascades under mild conditions, delivering complex aryl architectures with high chemoselectivity.
2-(Bromomethyl)-4-fluoro-1-nitrobenzene serves as a versatile bifunctional building block in synthetic organic chemistry, enabling efficient construction of complex heterocyclic scaffolds and pharmaceutical intermediates. The bromomethyl group facilitates nucleophilic substitution and palladium-catalyzed coupling reactions, while the fluorine and nitro groups provide orthogonal reactivity and enhanced electronic modulation. Its bench-stable nature and compatibility with standard purification methods make it well-suited for multi-step synthesis workflows in medicinal chemistry and process development.
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: