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Structure of 446-33-3
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5-Fluoro-2-nitrotoluene features a fluorine atom at the para position relative to a nitro group, creating a highly electron-deficient aromatic system. This strategic substitution enables selective electrophilic functionalization and serves as a key intermediate in pharmaceutical synthesis. The compound exhibits bench-stable handling characteristics and integrates readily into multi-step cascade reactions under standard conditions.
5-Fluoro-2-nitrotoluene serves as a versatile building block in synthetic organic chemistry, enabling the construction of fluorinated aromatic scaffolds through subsequent functionalization. Its ortho-nitro and para-fluoro substituents provide complementary reactivity for selective transformations, including reduction to the corresponding aniline derivative or transition-metal-catalyzed coupling reactions. The molecule exhibits good bench stability and is compatible with standard purification techniques, facilitating integration into multi-step syntheses for pharmaceutical intermediates and agrochemicals.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: