(S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methanamine

CAS No. 82954-65-2
Cat. No. CS-0094691
Purity≥95%
MDL No.MFCD03095390

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(S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methanamine|CS-0094691

Structure of 82954-65-2

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Description

(S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methanamine features a chiral dioxolane scaffold that delivers enhanced stability and solubility in polar solvents. This bench-stable building block integrates readily into asymmetric synthesis workflows, offering predictable stereocontrol in nucleophilic additions and coupling reactions.

Application

(S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methanamine serves as a stable, bench-ready chiral building block for asymmetric synthesis. Its protected hydroxyl group enables orthogonal functionalization, while the amine functionality facilitates nucleophilic substitution and peptide coupling reactions. The dioxolane ring provides excellent stability and solubility in common organic solvents, simplifying purification and handling in multi-step syntheses. This compound functions effectively in the construction of complex heterocycles and stereoselective intermediates.

General Information

CAS No. 82954-65-2
Cat. No. CS-0094691
Purity ≥95%
MDL No. MFCD03095390
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₃NO₂
Molecular Weight None
Synonym(s) (S)-4-AMINOMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE
SMILES NC[C@@H]1OC(C)(C)OC1

Computational Chemistry Data

TPSA 44.48
LogP 0.0966
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 1759
Class : 8	Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Dioxolane compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methanamine

CAS No. 82954-65-2

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