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Structure of 845267-72-3
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5-Azaspiro[2.5]octane-6,8-dione features a rigid spirocyclic core with dual ketone functionalities and a nitrogen atom embedded in the five-membered ring. This configuration imparts enhanced structural stability and polarity, enabling efficient integration into medicinal chemistry scaffolds. The molecule’s defined geometry supports predictable stereochemical outcomes in downstream transformations.
5-Azaspiro[2.5]octane-6,8-dione serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of spirocyclic scaffolds with defined stereochemistry. Its diketone functionality supports diverse transformations including reductive amination, nucleophilic addition, and condensation reactions, while the nitrogen atom enhances solubility and provides a handle for further derivatization. The rigid, three-dimensional structure contributes to favorable binding properties in target-directed synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: