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(4,6-Dimethylpyridin-3-yl)methanamine dihydrochloride

  • CAS No. 857220-05-4

  • Cat. No. CS-0280685
  • Molecule weight209.12
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4,6-Dimethylpyridin-3-yl)methanamine dihydrochloride|CS-0280685

Structure of 857220-05-4

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General Information

  • CAS No. 857220-05-4
  • Cat. No. CS-0280685
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₄Cl₂N₂
  • Molecular Weight 209.12
  • Synonym(s) [(4,6-dimethyl-3-pyridinyl)methyl]amine dihydrochloride
  • SMILES CC1=CC(C)=NC=C1CN.Cl.Cl

Description

This bench-stable, moisture-tolerant amine derivative features a pyridyl scaffold with electron-donating methyl groups that enhance nucleophilicity. It integrates readily into transition metal-catalyzed coupling reactions and serves as a key ligand precursor in palladium-mediated cross-coupling systems.

Application

(4,6-Dimethylpyridin-3-yl)methanamine dihydrochloride serves as a versatile building block in medicinal chemistry, enabling the construction of pyridine-based scaffolds through standard amine coupling reactions. Its bench-stable dihydrochloride salt form facilitates handling and purification, while the 4,6-dimethyl substitution pattern provides steric and electronic modulation for targeted molecular design. Functions effectively in nucleophilic substitution and reductive amination workflows, offering predictable reactivity in API and agrochemical intermediate synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   2.00074
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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