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CS-W001157 4
Total: USD 88.00

3-(4-(tert-Butoxycarbonyl)phenyl)propanoic acid

  • CAS No. 86208-18-6

  • Cat. No. CS-0343589
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(4-(tert-Butoxycarbonyl)phenyl)propanoic acid|CS-0343589

Structure of 86208-18-6

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General Information

  • CAS No. 86208-18-6
  • Cat. No. CS-0343589
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₈O₄
  • Molecular Weight 250.29
  • Synonym(s) None
  • SMILES O=C(O)CCC1=CC=C(C(OC(C)(C)C)=O)C=C1

Description

This 3-(4-(tert-butoxycarbonyl)phenyl)propanoic acid features a para-substituted phenyl ring linked to a carboxylic acid-bearing aliphatic chain, enabling integration into peptide conjugates and bioactive molecule scaffolds. The tert-butoxycarbonyl group provides temporary protection for amine functionalities during synthesis, offering stability under standard bench conditions and facilitating selective deprotection in downstream transformations.

Application

3-(4-(tert-Butoxycarbonyl)phenyl)propanoic acid serves as a versatile building block for the synthesis of biaryl-containing scaffolds and functionalized benzoic acid derivatives. The tert-butyl ester group provides excellent bench stability and facilitates orthogonal protection during peptide or heterocyclic assembly. It readily participates in standard coupling reactions, hydrogenation, and electrophilic transformations, enabling efficient access to complex molecular architectures relevant to medicinal chemistry and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   63.6
  • LogP   2.6591
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

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