Methyl 4-amino-2-methoxybenzoate

Name: Methyl 4-amino-2-methoxybenzoate
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CAS No. 27492-84-8
Cat. No. CS-M2604
Purity≥98%
MDL No.MFCD00017202

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Methyl 4-amino-2-methoxybenzoate|CS-M2604

Structure of 27492-84-8

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Description

Methyl 4-amino-2-methoxybenzoate features a para-amino group and ortho-methoxy substitution on the aromatic ring, delivering enhanced solubility and stability in polar solvents. This electron-rich scaffold integrates readily into synthetic routes for pharmaceutical intermediates and functional dyes, offering predictable reactivity under standard conditions.

Application

Methyl 4-amino-2-methoxybenzoate serves as a versatile synthetic intermediate in medicinal chemistry, enabling straightforward access to substituted anilines and heterocyclic scaffolds. Its ortho-methoxy group provides enhanced stability and facilitates selective functionalization, while the methyl ester offers a reliable handle for derivatization. The compound exhibits excellent bench stability and compatibility with standard coupling and reduction protocols, supporting efficient downstream transformations in API development workflows.

General Information

CAS No. 27492-84-8
Cat. No. CS-M2604
Purity ≥98%
MDL No. MFCD00017202
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₁NO₃
Molecular Weight 181.19
Synonym(s) Methyl 4-Amino-o-anisate
SMILES O=C(OC)C1=CC=C(N)C=C1OC

Computational Chemistry Data

TPSA 61.55
LogP 1.064
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

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Methyl 4-amino-2-methoxybenzoate

CAS No. 27492-84-8

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