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Structure of 882670-92-0
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6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinazolin-2-amine features a boronate ester handle attached to a quinazoline scaffold, enabling direct incorporation into Suzuki-Miyaura cross-coupling reactions. The tetramethyl-substituted dioxaborolane moiety ensures high stability and reactivity under standard conditions, while the electron-deficient quinazoline core supports efficient coupling with aryl halides. This structure delivers rapid access to complex heterocyclic architectures in medicinal chemistry and materials science.
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinazolin-2-amine serves as a versatile boronate building block for palladium-catalyzed cross-coupling reactions. The tetramethylboronate group enables efficient Suzuki-Miyaura coupling under mild conditions, facilitating the construction of biaryl and heteroaryl scaffolds. Its stability under ambient conditions, ease of purification, and compatibility with diverse functional groups make it a practical reagent for medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: