5-Chloro-1,4-dihydropyrimido[5,4-e][1,2,4]triazine

CAS No. 91115-01-4
Cat. No. CS-0089542
Molecule weight169.57
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Chloro-1,4-dihydropyrimido[5,4-e][1,2,4]triazine|CS-0089542

Structure of 91115-01-4

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 91115-01-4
Cat. No. CS-0089542
Purity ≥98%
MDL No. None
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₄ClN₅
Molecular Weight 169.57
Synonym(s) 5-Chloro-1,2-dihydropyrimido[5,4-e][1,2,4]triazine
SMILES ClC1=C2NC=NNC2=NC=N1

Description

5-Chloro-1,4-dihydropyrimido[5,4-e][1,2,4]triazine is a heterocyclic scaffold featuring a chlorinated pyrimidine core fused to a triazine ring. This electron-deficient system enables selective coupling reactions in medicinal chemistry and materials synthesis. The molecule exhibits bench-stable handling and compatibility with diverse functional groups, facilitating integration into complex molecular architectures.

Application

5-Chloro-1,4-dihydropyrimido[5,4-e][1,2,4]triazine serves as a versatile building block for constructing biologically relevant heterocyclic scaffolds. The chlorine atom at the 5-position enables efficient nucleophilic substitution, facilitating the introduction of diverse amine and thiol derivatives under mild conditions. Its stability under standard bench handling and compatibility with common protecting group strategies make it ideal for modular synthesis in medicinal chemistry and process development workflows.

Synthesis

Route1
- In-stock
  
  42786-59-4
- 149-73-5
- ~%
- In-stock
  
  91115-01-4
References
- SYNGENTA LIMITED; SYNGENTA PARTICIPATIONS AG Patent: WO2004/56829 A1, 2004 ; Location in patent: Page 76 ;
Route2
- 122-51-0
- In-stock
  
  42786-59-4
- ~73%
- In-stock
  
  91115-01-4
References
- Crowley, Patrick J.; Lamberth, Clemens; Mueller, Urs; Wendeborn, Sebastian; Sageot, Olivia-A.; Williams, John; Bartovic, Alexander Tetrahedron Letters, 2010 , vol. 51, # 19 p. 2652 - 2654

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 62.2
LogP 0.9107
H_Acceptors 5
H_Donors 2
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

91115-01-4 sigma91115-01-4 manufacturer91115-01-4 price91115-01-4 structure91115-01-4 SDSbuy 91115-01-491115-01-4 supplier91115-01-4 uses91115-01-4 molecular weightprice of 91115-01-491115-01-4 chemical name formula of 91115-01-4

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5-Chloro-1,4-dihydropyrimido[5,4-e][1,2,4]triazine

CAS No. 91115-01-4

Recommended Products