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Structure of 914988-10-6
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tert-Butyl 3-cyano-4-oxopiperidine-1-carboxylate features a sterically shielded tert-butyl ester paired with a conjugated cyano-ketone motif, enabling direct incorporation into complex heterocyclic scaffolds. This bench-stable intermediate facilitates efficient access to nitrogen-containing frameworks through reductive amination or nucleophilic addition pathways.
tert-Butyl 3-cyano-4-oxopiperidine-1-carboxylate serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted piperidines via reductive amination or nucleophilic addition. The cyano and oxo groups offer orthogonal reactivity for downstream functionalization, while the tert-butyl carbamate provides excellent bench stability and ease of removal under mild acidic conditions. Its well-defined stereochemistry and compatibility with standard coupling protocols make it ideal for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P304+P341-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P363-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: