tert-Butyl (2-chloroethyl)(methyl)carbamate

Name: tert-Butyl (2-chloroethyl)(methyl)carbamate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 220074-38-4
Cat. No. CS-0133123
Purity≥97%
MDL No.MFCD20624610

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (2-chloroethyl)(methyl)carbamate|CS-0133123

Structure of 220074-38-4

Size

Price

Quantity

* Please select Quantity before adding items.

Description

tert-Butyl (2-chloroethyl)(methyl)carbamate features a chloroethyl group flanked by a methylamino and tert-butyl carbamate moiety, enabling selective alkylation under mild conditions. This bench-stable reagent integrates cleanly into peptide synthesis workflows, delivering controlled functionalization with minimal side reactions.

Application

tert-Butyl (2-chloroethyl)(methyl)carbamate serves as a versatile, bench-stable carbamate protecting group for primary amines, enabling selective N-alkylation and subsequent deprotection under mild acidic conditions. Its chlorine-bearing side chain facilitates nucleophilic substitution reactions, making it valuable in the synthesis of functionalized amino acids, peptide analogs, and heterocyclic scaffolds. The tert-butyl group ensures excellent stability during standard organic transformations and simplifies purification through its low polarity and volatility upon acid cleavage.

General Information

CAS No. 220074-38-4
Cat. No. CS-0133123
Purity ≥97%
MDL No. MFCD20624610
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₆ClNO₂
Molecular Weight 193.67
Synonym(s) tert-butyl N-(2-chloroethyl)-N-methylcarbamate
SMILES ClCCN(C(OC(C)(C)C)=O)C

Computational Chemistry Data

TPSA 29.54
LogP 2.0921
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 3265
Class : 8	Packing Group : Ⅲ
Hazard Statements : H302-H315-H318
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Chloride

Building Blocks Skeleton Fatty chain compounds

Key Words

220074-38-4 sigma220074-38-4 manufacturer220074-38-4 price220074-38-4 structure220074-38-4 SDSbuy 220074-38-4220074-38-4 supplier220074-38-4 uses220074-38-4 molecular weightprice of 220074-38-4220074-38-4 chemical name formula of 220074-38-4

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

tert-Butyl (2-chloroethyl)(methyl)carbamate

CAS No. 220074-38-4

Recommended Products