6-Bromoimidazo[1,2-a]pyridin-2-amine

CAS No. 947248-52-4
Cat. No. CS-0040344
Purity≥96%
MDL No.MFCD09864902

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6-Bromoimidazo[1,2-a]pyridin-2-amine|CS-0040344

Structure of 947248-52-4

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Description

6-Bromoimidazo[1,2-a]pyridin-2-amine features a fused heterocyclic core with a bromine at the 6-position and an amine group at the 2-position. This combination enables direct functionalization in cross-coupling reactions and facilitates incorporation into bioactive scaffolds. The molecule exhibits stability under standard handling conditions and serves as a key intermediate in medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.

Application

6-Bromoimidazo[1,2-a]pyridin-2-amine serves as a versatile building block for constructing biologically relevant heterocyclic scaffolds. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, while the imidazopyridine core provides structural rigidity and favorable pharmacophoric properties. The compound exhibits good bench stability and facilitates efficient functionalization in medicinal chemistry campaigns.

General Information

CAS No. 947248-52-4
Cat. No. CS-0040344
Purity ≥96%
MDL No. MFCD09864902
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆BrN₃
Molecular Weight 212.05
Synonym(s) 6-BROMO-IMIDAZO[1,2-A]PYRIDIN-2-AMINE
SMILES NC1=CN2C=C(Br)C=CC2=N1

Computational Chemistry Data

TPSA 43.32
LogP 1.679
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Key Words

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6-Bromoimidazo[1,2-a]pyridin-2-amine

CAS No. 947248-52-4

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