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Di-tert-butyl (2-hydroxypropane-1,3-diyl)dicarbamate

  • CAS No. 98642-15-0

  • Cat. No. CS-0154398
  • Molecule weight290.36
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Di-tert-butyl (2-hydroxypropane-1,3-diyl)dicarbamate|CS-0154398

Structure of 98642-15-0

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General Information

  • CAS No. 98642-15-0
  • Cat. No. CS-0154398
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₆N₂O₅
  • Molecular Weight 290.36
  • Synonym(s) tert-butyl N-{3-[(tert-butoxycarbonyl)amino]-2-hydroxypropyl}carbamate
  • SMILES CC(C)(OC(NCC(O)CNC(OC(C)(C)C)=O)=O)C

Description

Di-tert-butyl (2-hydroxypropane-1,3-diyl)dicarbamate serves as a stable, moisture-tolerant protecting group for diol functionalities. This bifunctional reagent integrates seamlessly into complex molecule synthesis, enabling selective protection under mild conditions. The tert-butyl carbamate moieties offer robust stability while the hydroxypropane backbone provides strategic spatial positioning for downstream transformations.

Application

Di-tert-butyl (2-hydroxypropane-1,3-diyl)dicarbamate serves as a stable, bench-ready protecting group for vicinal diols and amino-alcohols. It facilitates selective protection in complex molecule synthesis, enabling orthogonal deprotection strategies. The molecule exhibits excellent functional group tolerance and simplifies purification due to its high stability under standard reaction conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   96.89
  • LogP   1.3967
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   4

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