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CS-W001157 4
Total: USD 88.00

1-Chloroethyl cyclohexyl carbonate

  • CAS No. 99464-83-2

  • Cat. No. CS-W015297
  • Molecule weight206.67
  • Purity≥98%
  • MDL No.MFCD04038149

*For research and further manufacturing use only, not for direct human use.

1-Chloroethyl cyclohexyl carbonate|CS-W015297

Structure of 99464-83-2

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General Information

  • CAS No. 99464-83-2
  • Cat. No. CS-W015297
  • Purity ≥98%
  • MDL No. MFCD04038149
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₅ClO₃
  • Molecular Weight 206.67
  • Synonym(s) cycylhexyl-1-chloro ethyl carbonate; 1-Chloroethyl cyclohexyl carbonate
  • SMILES O=C(OC(Cl)C)OC1CCCCC1

Description

1-Chloroethyl cyclohexyl carbonate serves as a stable, moisture-tolerant protecting group for alcohols and thiols. This reagent features a chloroethyl moiety that enables selective activation under mild conditions, facilitating efficient deprotection without side reactions. The cyclohexyl carbonate backbone enhances solubility in organic media while maintaining bench stability. It integrates seamlessly into synthetic sequences requiring orthogonal protection strategies.

Synthesis

  • Route1
    • null|null
      50893-53-3
    • In-stock
      1-Cyclohexanol|CS-0017198
      108-93-0
    • ~91%
    • In-stock
      1-Chloroethyl cyclohexyl carbonate|CS-W015297
      99464-83-2

    References

    • ANCHEN LABORATORIES, INC Patent: WO2009/118580 A2, 2009 ; Location in patent: Page/Page column 17-18 ;
  • Route2
    • null|null
      75-07-0
    • null|null
      13248-54-9
    • ~%
    • In-stock
      1-Chloroethyl cyclohexyl carbonate|CS-W015297
      99464-83-2

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 14 p. 1921 - 1926

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.53
  • LogP   3.0571
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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