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CS-W001157 4
Total: USD 88.00

(S,S)-Me-DUPHOS

  • CAS No. 136735-95-0

  • Cat. No. CS-0086465
  • Molecule weight306.36
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S,S)-Me-DUPHOS|CS-0086465

Structure of 136735-95-0

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General Information

  • CAS No. 136735-95-0
  • Cat. No. CS-0086465
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₂₈P₂
  • Molecular Weight 306.36
  • Synonym(s) Methyl-duphos, (S,S)-
  • SMILES C[C@@H](CC[C@@H]1C)P1C2=CC=CC=C2P3[C@@H](C)CC[C@@H]3C

Description

DuPhos and BPE Ligands: Highly Efficient Privileged Ligands

Application

(S,S)-Me-DUPHOS serves as a highly effective chiral bidentate ligand in transition-metal-catalyzed asymmetric reactions, particularly in palladium- and rhodium-catalyzed hydrogenations and allylic alkylations. Its rigid backbone and defined stereochemistry enable high enantioselectivity in established synthetic protocols. The methylated diphosphine structure enhances steric control and bench stability, facilitating straightforward handling and purification. Widely employed in medicinal chemistry and process development, it functions reliably across diverse substrate classes requiring precise stereocontrol.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   5.0426
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   2

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