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CS-W001157 4
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tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate

  • CAS No. 236406-55-6

  • Cat. No. CS-D0149
  • Molecule weight226.32
  • Purity≥95%
  • MDL No.MFCD09834803

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate|CS-D0149

Structure of 236406-55-6

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General Information

  • CAS No. 236406-55-6
  • Cat. No. CS-D0149
  • Purity ≥95%
  • MDL No. MFCD09834803
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₂N₂O₂
  • Molecular Weight 226.32
  • Synonym(s) None
  • SMILES O=C(N1CC2(CCNCC2)C1)OC(C)(C)C

Description

tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate is a sterically shielded spirocyclic amine derivative featuring a protected diamine core. This bench-stable scaffold integrates a tert-butyl ester group for orthogonal deprotection, enabling efficient access to functionalized heterocycles in medicinal chemistry and catalyst design.

Application

tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate serves as a versatile scaffold for the synthesis of spirocyclic heterocycles, offering robust bench stability and compatibility with standard functional group manipulations. The protected diamine core facilitates selective derivatization at nitrogen atoms and enables efficient incorporation into medicinal chemistry libraries via amide bond formation or reductive amination. Its rigid spiro architecture supports conformational constraint in target molecules, enhancing binding affinity and metabolic stability.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   1.6069
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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