IL-17A
IL-17A is a pro-inflammatory cytokine produced by T helper 17 (Th17) cells, playing a crucial role in immune responses, particularly in the defense against pathogens and in autoimmune diseases. It promotes the recruitment of neutrophils and the release of other cytokines, amplifying inflammation. Dysregulation of IL-17A signaling is associated with several chronic inflammatory conditions, such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease. Targeting IL-17A or its receptor has shown therapeutic potential in treating these diseases by reducing inflammation and preventing tissue damage, making it an attractive target for immune-modulatory therapies.
Technical Resources
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Catalytic asymmetric Friedel–Crafts alkylation of unprotected indoles with nitroalkenes using a novel chiralChiral chloro-indeno pybox has served as a new ligand for the Yb(OTf)3-catalyzed asymmetric Friedel–Crafts alkylation reaction of indoles with nitroalkenes. The tunable nature of pybox ligands
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2Catalytic asymmetric Friedel–Crafts alkylation of unprotected indoles with nitroalkenes using a novel chiral
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3Catalytic asymmetric Friedel–Crafts alkylation of unprotected indoles with nitroalkenes using a novel chiral
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4Catalytic asymmetric Friedel–Crafts alkylation of unprotected indoles with nitroalkenes using a novel chiral
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5Catalytic asymmetric Friedel–Crafts alkylation of unprotected indoles with nitroalkenes using a novel chiral
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In-stockPurity: ≥95%
Cat. No. : CS-0498540CAS No. : 1083246-26-7* This product is not sold in the region.
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In-stockPurity: ≥98%
Cat. No. : CS-0498561CAS No. : 2452465-34-6* This product is not sold in the region.
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Cat. No. : CS-0533685 -
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In-stockPurity: ≥98%
Cat. No. : CS-0541673 -
In-stockPurity: ≥97%
Cat. No. : CS-0648666CAS No. : 1896825-76-5* This product is not sold in the region.
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In-stockPurity: ≥98%
Cat. No. : CS-0783976CAS No. : 2735653-64-0* This product is not sold in the region.
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In-stockPurity: ≥98%
Cat. No. : CS-0885637CAS No. : 1806421-58-8* This product is not sold in the region.