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CS-W001157 4
Total: USD 88.00

3-Bromotetrahydrofuran

  • CAS No. 19311-37-6

  • Cat. No. CS-W004035
  • Molecule weight151.00
  • Purity≥95%
  • MDL No.MFCD09056777

*For research and further manufacturing use only, not for direct human use.

3-Bromotetrahydrofuran|CS-W004035

Structure of 19311-37-6

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General Information

  • CAS No. 19311-37-6
  • Cat. No. CS-W004035
  • Purity ≥95%
  • MDL No. MFCD09056777
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇BrO
  • Molecular Weight 151.00
  • Synonym(s) None
  • SMILES BrC1COCC1

Description

3-Bromotetrahydrofuran is a reactive, bench-stable heterocyclic building block featuring a pendant bromide at the 3-position. This electrophilic site enables efficient coupling reactions in synthetic sequences, particularly in transition-metal-catalyzed transformations. The saturated furan ring provides structural rigidity and enhanced solubility in common organic solvents.

Application

3-Bromotetrahydrofuran serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized heterocycles and pharmaceutical intermediates. Its well-established reactivity facilitates nucleophilic substitution and transition-metal-catalyzed coupling reactions, offering high regioselectivity and compatibility with diverse functional groups. The compound exhibits excellent bench stability and is readily purified by standard techniques, making it ideal for scalable synthesis and iterative molecular construction in medicinal and process chemistry workflows.

Synthesis

  • Route1

    References

    • Bendall, Justin G.; Payne, Andrew N.; Screen, Thomas E. O.; Holmes, Andrew B. Chemical Communications, 1997 , # 11 p. 1067 - 1068
  • Route2
    • null|null
      627-27-0
    • ~48%
    • In-stock
      3-Bromotetrahydrofuran|CS-W004035
      19311-37-6
    • null|null
      87018-30-2

    References

    • Russian Chemical Bulletin, , vol. 61, # 2 p. 459 - 463 Izv. Akad. Nauk, Ser. Khim., , # 2 p. 456 - 460,5
  • Route3
    • null|null
      627-27-0
    • ~94%
    • In-stock
      3-Bromotetrahydrofuran|CS-W004035
      19311-37-6

    References

    • Nikishin; Sokova; Kapustina Russian Chemical Bulletin, 2012 , vol. 61, # 2 p. 459 - 463 Izv. Akad. Nauk, Ser. Khim., 2012 , # 2 p. 456 - 460,5

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501

Quality Control

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   1.1702
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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