Structurally Diverse Fragment Library
| Cat. No. : CS-L187 |
|---|
| （2,258） |
| Library Contents: |
| Fragment-based drug development (FBDD) is a strategy for drug discovery that can be applied both academically and commercially to enhance the identification of some non-drug targets. Fragment-based drug development has identified low molecular weight molecules (<300 Da) capable of binding to related macromolecules. These fragments can cover a wide chemical space and are easy to optimize later. Currently, several fragment-based drugs have entered clinical trials, of which two drugs, Vemurafenib and Venetoclax, have been approved for marketing. Based on Tanimoto coefficient, ChemScene uses similarity algorithm to carefully select 2,258 high-structurally diverse 'RO3' compliant fragment molecules from large-scale fragment molecules, which can be applied to fragment based drug development. |
| Size (Pre-dissolved DMSO or Solid) | Stock | Price |
|---|---|---|
| In-stock | Get quote |
Products are for research use only. Not for human use. We do not sell to patients.
Bulk Inquiry
CollapseYour information is safe with us. * Required Fields
Data Sheet
Description & Advantages
Composition
| Formulation: | A collection of 2,258 fragments as pre-dissolved solutions or solid. |
|---|---|
| Container: | 96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode |
| Storage: | -80°C |
| Shipping: | Blue ice or dry ice |
• A unique collection of 2,258 high diversity fragments for high throughput screening (HTS) and high content screening (HCS).
• Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.
• Structurally diverse, bioactive, and cell permeable.
• More detailed compound information with structure, IC50, and other chemical & biological data.
• High purity and quality validated by NMR and LC/MS.
• All compounds are in stock and continuously updated.
Browsing History
| Tags:Structurally Diverse Fragment Library supplier, Structurally Diverse Fragment Library purchase, Structurally Diverse Fragment Library manufacturer, Structurally Diverse Fragment Library sigma, Structurally Diverse Fragment Library distributor, cost, Structurally Diverse Fragment Library buy, Structurally Diverse Fragment Library for sale |