Lead-like Diversity Library Plus
| Cat. No. : CS-L901P |
|---|
| （80,000） |
| Library Contents: |
| A Lead-like, diverse library is the foundation for achieving biological activity diversity. The ChemScene Lead-like Diverse Library Plus is a further supplement to the 50K Lead-like Compound Library (HY-L901), consisting of over 80,000 lead-like compounds, with an additional 30,000 structurally novel lead-like molecules. These compounds occupy a broader "chemical space", making it a powerful tool for new drug discovery. |
| Size (Pre-dissolved DMSO or Solid) | Stock | Price |
|---|---|---|
| In-stock | Get quote |
Bulk Inquiry
CollapseData Sheet
Description & Advantages
Composition
| Formulation: | Consisting of over 80,000 compounds with 50,000 scaffolds (Bemis-Murcko). |
|---|---|
| Container: | 96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode. |
| Storage: | -80°C |
| Shipping: | Blue ice or dry ice |
• Compounds in this library with a high divesity and broad chemical space coverage.
• Mostly compatible with “Lipinski’s Rule of Five”, with multiple characteristics such as calculated good permeability (-3.2 < logP < 5), oral bioavailability (RotB <= 10), drug transportability (PSA < 120), MW between 300 to 500, number of Hydrogen Bond Donor (HBD) ≤ 5, number of Hydrogen Bond Acceptor (HBA) ≤ 10.
• Passed all associated MedChem filters, particularly pan assay interference compound (PAINS) motifs, to remove any inappropriate chemical structures and avoid false hits.
• All compounds are available off the shelf. Pre-plates of 10 mM DMSO solutions, convenient to use.
• LCMS or NMR validated to ensure high purity and quality.
| Tags:Lead-like Diversity Library Plus supplier, Lead-like Diversity Library Plus purchase, Lead-like Diversity Library Plus manufacturer, Lead-like Diversity Library Plus sigma, Lead-like Diversity Library Plus distributor, cost, Lead-like Diversity Library Plus buy, Lead-like Diversity Library Plus for sale |