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Structure of 1000342-93-7
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4-Bromo-6-(trifluoromethyl)-1H-indole features a sterically accessible indole core functionalized with a bromine at C4 and a trifluoromethyl group at C6, enabling direct coupling in cross-coupling reactions. The electron-deficient nature of the trifluoromethyl substituent enhances reactivity in palladium-catalyzed transformations. This compound serves as a key building block for bioactive heterocycles in medicinal chemistry and materials science.
4-Bromo-6-(trifluoromethyl)-1H-indole serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. Its bromo group enables palladium-catalyzed cross-coupling reactions, while the trifluoromethyl moiety enhances metabolic stability and lipophilicity. The molecule exhibits excellent bench stability and facilitates efficient functionalization in standard coupling protocols, making it well-suited for constructing complex indole-based scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: