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Structure of 1000576-23-7
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This indazole carboxylic acid features a tetrahydropyran-2-yl protecting group that confers enhanced solubility and stability under standard conditions. The scaffold integrates a polar heterocyclic core with a robust, moisture-tolerant functionality suitable for synthetic intermediates in medicinal chemistry.
1-(Tetrahydro-2H-pyran-2-yl)-1H-indazole-4-carboxylic acid serves as a versatile building block for indazole-based scaffolds, enabling direct incorporation into medicinal chemistry campaigns. The tetrahydropyranyl (THP) group provides robust protection of the carboxylic acid under standard reaction conditions, facilitating orthogonal functionalization and simplifying purification. This derivative exhibits excellent bench stability and compatibility with common coupling protocols, making it ideal for iterative synthesis of bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: