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CS-W001157 4
Total: USD 88.00

5-(Tetrahydro-2H-pyran-4-yl)-1H-pyrazol-3-amine

  • CAS No. 1000896-69-4

  • Cat. No. CS-0120134
  • Molecule weight167.21
  • Purity≥96%
  • MDL No.MFCD20502055

*For research and further manufacturing use only, not for direct human use.

5-(Tetrahydro-2H-pyran-4-yl)-1H-pyrazol-3-amine|CS-0120134

Structure of 1000896-69-4

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General Information

  • CAS No. 1000896-69-4
  • Cat. No. CS-0120134
  • Purity ≥96%
  • MDL No. MFCD20502055
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₃N₃O
  • Molecular Weight 167.21
  • Synonym(s) None
  • SMILES NC1=NNC(C2CCOCC2)=C1

Description

This pyrazole derivative features a tetrahydro-pyran-4-yl substituent that enhances solubility and metabolic stability. The primary amine group enables straightforward functionalization, while the heterocyclic core supports integration into bioactive scaffolds. Designed for efficient incorporation in medicinal chemistry campaigns.

Application

5-(Tetrahydro-2H-pyran-4-yl)-1H-pyrazol-3-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to functionalized pyrazole scaffolds. The tetrahydropyran-4-yl group provides excellent bench stability and solubility, while the primary amine facilitates straightforward derivatization via amidation, alkylation, or coupling reactions. Its compatibility with standard synthetic protocols makes it a practical choice for constructing heterocyclic libraries and API intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   63.93
  • LogP   0.8859
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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