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Structure of 1001056-83-2
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3-Bromo-4,5-dichloropyridine features a highly reactive pyridine core bearing bromo and two chloro substituents at strategic positions, enabling selective cross-coupling in late-stage functionalization. The electron-deficient ring facilitates palladium-catalyzed transformations, while the orthogonal halogen reactivity supports sequential derivatization. This scaffold serves as a key building block for bioactive heterocycles in medicinal chemistry and agrochemical development.
3-Bromo-4,5-dichloropyridine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient late-stage functionalization via Pd-catalyzed cross-coupling reactions. The bromo group facilitates selective coupling under standard conditions, while the flanking chlorides enhance electrophilicity and provide orthogonal reactivity for sequential transformations. Its bench-stable nature and compatibility with diverse reaction conditions make it a practical choice for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: