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CS-W001157 4
Total: USD 88.00

3-Bromo-4-chloropyridine

  • CAS No. 36953-42-1

  • Cat. No. CS-M3246
  • Purity≥95%
  • MDL No.MFCD00234008
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Bromo-4-chloropyridine|CS-M3246

Structure of 36953-42-1

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Description

3-Bromo-4-chloropyridine is a halogenated pyridine derivative featuring complementary reactive sites for cross-coupling and functionalization. This electron-deficient heterocycle integrates readily into synthetic sequences requiring orthogonal substitution patterns. Its bench-stable nature supports reliable handling in transition metal-catalyzed transformations and medicinal chemistry applications.

Application

3-Bromo-4-chloropyridine serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The bromo group facilitates Suzuki, Stille, or Negishi coupling, while the chloro substituent offers stability under reaction conditions. This compound exhibits excellent bench stability and ease of purification, making it well-suited for iterative synthesis of complex heterocyclic scaffolds and API intermediates.

General Information

  • CAS No. 36953-42-1
  • Cat. No. CS-M3246
  • Purity ≥95%
  • MDL No. MFCD00234008
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃BrClN
  • Molecular Weight None
  • Synonym(s) 4-CHLORO-3-BROMOPYRIDINE
  • SMILES ClC1=C(Br)C=NC=C1

Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.4975
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H318-H335
Precautionary Statements : P261-P264-P264-P280-P302+P352

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