(4-Aminopyridin-2-yl)methanol

Name: (4-Aminopyridin-2-yl)methanol
Brand: ChemScene
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CAS No. 100114-58-7
Cat. No. CS-0039297
Purity≥95%
MDL No.MFCD11100581

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(4-Aminopyridin-2-yl)methanol|CS-0039297

Structure of 100114-58-7

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Description

(4-Aminopyridin-2-yl)methanol features a pyridine ring bearing both an amino group at the 4-position and a hydroxymethyl substituent at the 2-position, delivering a bifunctional scaffold with enhanced solubility and synthetic versatility. This bench-stable compound integrates readily into medicinal chemistry campaigns requiring polar, nitrogen-rich motifs for target engagement or derivatization.

Application

(4-Aminopyridin-2-yl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyridine-based scaffolds. Its dual functionality—primary amine and primary alcohol—facilitates diverse transformations including amidation, etherification, and cyclization reactions. The compound exhibits good bench stability and is compatible with standard protection/deprotection sequences, making it well-suited for multi-step synthesis and API development workflows.

General Information

CAS No. 100114-58-7
Cat. No. CS-0039297
Purity ≥95%
MDL No. MFCD11100581
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₈N₂O
Molecular Weight 124.14
Synonym(s) 2-METHOXY-PYRIDIN-4-YLAMINE
SMILES OCC1=NC=CC(N)=C1

Computational Chemistry Data

TPSA 59.14
LogP 0.1561
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 1

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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(4-Aminopyridin-2-yl)methanol

CAS No. 100114-58-7

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