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Structure of 1001419-35-7
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tert-Butyl (4-(bromomethyl)thiazol-2-yl)carbamate delivers a bromomethyl-functionalized thiazole scaffold with a robust carbamate protecting group. This reagent integrates readily into synthetic sequences, enabling direct substitution at the thiazole C4 position. The pendant bromide serves as a high-affinity electrophile for nucleophilic displacement reactions, facilitating rapid access to complex heterocyclic architectures under mild conditions.
tert-Butyl (4-(bromomethyl)thiazol-2-yl)carbamate serves as a versatile building block for thiazole-based scaffolds, enabling efficient late-stage functionalization via SN2 displacement. The bromomethyl group facilitates reliable coupling with nucleophiles, while the tert-butyl carbamate provides orthogonal protection and excellent bench stability. Its compatibility with standard cross-coupling protocols and ease of deprotection make it ideal for medicinal chemistry campaigns targeting heterocyclic APIs.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H302-H314
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Precautionary Statements : P264-P270-P271-P280-P304+P340-P330-P331-P363-P501
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Lot numbers can be found on the outside label of a product: